Artificial Metalloenzymes Laboratory
Endowing Organometallic Chemistry with a (Genetic) Memory
Artificial metalloenzymes result from the incorporation of an abiotic cofactor within a protein scaffold. Such hybrid catalysts combine features reminiscent of both homogeneous catalysts and enzymes.
Merging organometallic chemistry with biotechnology
Organometallic- and enzymatic catalysis have evolved independently over the past four decades. By incorporating an organometallic moiety within a protein host, we create artificial metallo-enzymes, with properties reminiscent both of homogeneous and enzymatic catalysis.